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Finnegan
Xirui Zhang, Ph.D.
Associate
More
vCard
  • Two Seaport Lane
  • Boston, MA 02210-2001
+1 617 646 1626
xirui.zhang@finnegan.com xirui.zhang@finnegan.com

Xirui Zhang, Ph.D.

Associate

  • +1 617 646 1626 +1 617 646 1626
  • xirui.zhang@finnegan.com xirui.zhang@finnegan.com
  • Two Seaport Lane
  • Boston, MA 02210-2001
  • vCard

Xirui Zhang, Ph.D., focuses her practice on strategic counseling, patent prosecution, and post-grant proceedings before the Patent Trial and Appeal Board (PTAB) of the U.S. Patent and Trademark Office (USPTO).

Xirui has worked on over 20 inter partes review (IPR) proceedings, representing both petitioners and patent owners. She has experience searching prior art, developing validity strategy, crafting effective briefing, preparing expert and lay witnesses, and arguing in oral hearing.

Xirui's practice extends to evaluations for diligence, clearance, landscape, freedom-to-operate, and design-around assessments. She provides legal opinions on infringement, validity, and patentability. Xirui also advises clients through all stages of preparation and prosecution of U.S. utility and design patent applications, including handling invention disclosures; preparing new and continuing patent applications; responding to office actions; preparing and filing appeals to the PTAB; and managing domestic and international portfolios aligned with client business goals.

Xirui's experience spans numerous technologies, including medical and analytical devices, optical microscopy and spectroscopy, optical biosensing, optoelectronics, optical coherence tomography, endoscopy, magnetic resonance imaging, ultrasound imaging, image and video processing, nanotechnology, in vitro molecular diagnostics, consumer electronics, mobile devices, digital camera, electronic authentication, LED lighting systems, robotics, neurostimulation and neuromodulation, 3D printing and additive manufacturing, virtual and augmented reality, computer processor, power tools, and artificial intelligence (AI) technologies in medicine.

Before joining Finnegan, Xirui completed her doctoral research in the Optical Characterization and Nanophotonics (OCN) laboratory at the Photonics Center of Boston University, where she built high-throughput optical biosensing instruments for molecular research and point-of-care diagnosis.Her collaboration with scientists and engineers during her studies strengthens her ability to work with inventors and experts on technical intricacies in her patent practice.

Et Cetera

  • Coauthor.  "Quantitative Characterization of Conformational-Specific Protein-DNA Binding Using a Dual-Spectral Interferometric Imaging Biosensor," Nanoscale, 2016.
  • Coauthor.  "DNA-Directed Antibody Immobilization for Enhanced Detection of Single Viral Pathogens," Analytical Chemistry, 2015.
  • Coauthor.  "Characterization of Nanoscale DNA Conformation by Dual-Color Fluorescent Axial Localization and Label-Free Biosensing Arrays," Analyst, 2014.
  • Coauthor.  "Spectral Self-Interference Fluorescence Microscopy to Study Conformation of Biomolecules with Nanometer Accuracy," Nanoscale Spectroscopy with Applications, 2013.
  • Coauthor.  "High-Throughput Label-Free Detection of DNA Hybridization and Mismatch Discrimination Using Interferometric Reflectance Imaging Sensor," Methods in Molecular Biology, 2013.
  • Coauthor.  "Precisely Controlled Smart Polymer Scaffold for Nanoscale Manipulation of Biomolecules," Analytical Chemistry, 2012.
  • Coauthor.  "TATA Binding Proteins Can Recognize Nontraditional DNA Sequences," Biophysical Journal, 2012.
  • Coauthor.  "High-Throughput Detection and Sizing of Individual Low-Index Nanoparticles and Viruses for Pathogen Identification," Nano Letters, 2010.

Insights

Articles

Unpacking Squires’ Recent Discretionary Denial Guidance Focusing on American Manufacturing

Unpacking Squires’ Recent Discretionary Denial Guidance Focusing on American Manufacturing Unpacking Squires’ Recent Discretionary Denial Guidance Focusing on American Manufacturing

April 24, 2026

Intellectual Asset Management (IAM)

Articles

Trending at the PTAB: The Policies That Are Redefining IPR

Trending at the PTAB: The Policies That Are Redefining IPR Trending at the PTAB: The Policies That Are Redefining IPR

January 6, 2026

Law360

Articles

Trending at the PTAB: The Journey of IPR Institution in 2025

Trending at the PTAB: The Journey of IPR Institution in 2025 Trending at the PTAB: The Journey of IPR Institution in 2025

January 5, 2026

Law360

Workshop

IP 101 for Robotics Startups IP 101 for Robotics Startups

April 17, 2024

Boston

Articles

Trending at the PTAB: 6 Areas to Watch in 2024

Trending at the PTAB: 6 Areas to Watch in 2024 Trending at the PTAB: 6 Areas to Watch in 2024

January 2, 2024

Law360

Articles

How the PTAB Landscape Shifted in 2023

How the PTAB Landscape Shifted in 2023 How the PTAB Landscape Shifted in 2023

December 15, 2023

Law360
More

News

Press Release

Judge Albright Issues Ex Parte TRO Blocking Foreign Efforts to Interfere with U.S. Patent Jurisdiction in BMW Case Judge Albright Issues Ex Parte TRO Blocking Foreign Efforts to Interfere with U.S. Patent Jurisdiction in BMW Case

December 17, 2025

Press Release

Action Filed to Prevent Foreign Courts from Deciding U.S. Patent Claims Action Filed to Prevent Foreign Courts from Deciding U.S. Patent Claims

December 15, 2025

Media Mention

BMW Texas Suit Accuses Patent Owner of Forum Shopping in Germany BMW Texas Suit Accuses Patent Owner of Forum Shopping in Germany

December 15, 2025

Bloomberg Law

Award/Ranking

Best Lawyers Recognizes 44 Finnegan Attorneys in its 2026 Edition of The Best Lawyers and Ones to Watch Best Lawyers Recognizes 44 Finnegan Attorneys in its 2026 Edition of The Best Lawyers and Ones to Watch

August 21, 2025

Best Lawyers

Press Release

Finnegan Wins Again for BMW Against Atlantic IP, This Time at the PTAB Finnegan Wins Again for BMW Against Atlantic IP, This Time at the PTAB

March 28, 2025

Professional Activities

  • American Intellectual Property Law Association (AIPLA)
  • Biomedical Engineering Society
  • Boston Intellectual Property Law Association
  • Boston Patent Law Association
  • PTAB Bar Association
  • The Optical Society of America
Admissions and Education

Admissions

  • U.S. Patent and Trademark Office
  • Massachusetts
  • U.S. District Court, D. Massachusetts

Education

Boston College Law School
J.D., 2019
Boston University
Ph.D., Biomedical Engineering, 2014
Tianjin University
B.S., Biomedical Engineering, 2009
Tianjin University
B.A., English, 2009

Languages

  • Chinese (Mandarin)

Xirui's Practices

AI + Finnegan
AI + Patent
Diligence, Licensing, and Opinions
Due Diligence
Freedom to Operate Opinions
Licensing, Pooling, and Other Transactions
Opinions and Counseling
Patent Mining and Mapping
Global IP Enforcement, Litigation, and Trials
Antitrust and Misuse
Patent Office Invalidation Proceedings
Ex Parte Reexamination (EPR)
PTAB Invalidation Proceedings: IPR and PGR
Prosecution and Portfolio Management
Appeals to the PTAB
Design Rights
IP Portfolio Management
Patent Drafting and Prosecution
Patent Reissues

Xirui's Industries

AI, Electronics, and Information Technology
Artificial Intelligence (AI) and Machine Learning (ML)
Augmented Reality/Virtual Reality (AR/VR)
Electrical and Computer Technology
Electronic Devices and Components
Robotics
Chemicals, Industrials, and Materials
Additive Manufacturing
Communications
Financial Services and Business Systems
Consumer Goods and Services
Consumer Products
Life Sciences
Biotechnology
Digital Health
Medical Device and Diagnostics

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