Partner
Jeffrey Jacobstein, managing partner of Finnegan’s Boston office, brings more than 15 years of experience in high-stakes transactions, sophisticated counseling, and successful resolution of contentious proceedings to his practice with clients in the biotechnology and life science spaces.
Jeffrey focuses on strategic client counseling, including due diligence, patent prosecution, and post-grant proceedings, with an emphasis on biotechnology and life sciences. He has led teams handling all intellectual property (IP)-related aspects of multi-billion dollar deals for several large pharmaceutical clients. His experience also includes prosecuting and appealing applications within the U.S. Patent and Trademark Office (USPTO), as well as larger portfolio management, diligence, licensing, and opinion work. Jeffrey has been recognized by LMG Life Sciences as Patent Strategy Attorney of the Year, New England, and honored for his contributions to the fields of “Patent Strategy & Management” and “Patent Prosecution.” He has also been identified by The Legal 500 U.S. as one of the leading lawyers in patent prosecution. Jeffrey previously served as leader of the firm’s patent office practice.
Jeffrey has conducted hundreds of evaluations for acquisition, partnership, diligence, clearance, and freedom-to-operate (FTO) assessments, and has extensive experience providing patentability, validity, enforceability, and infringement opinions. He has drafted and successfully prosecuted many new patent applications in the United States and various international jurisdictions, advising clients on all aspects of portfolio management along the way. Jeffrey also plans for and acquires patent term extensions (PTEs) and supplemental protection certificates (SPCs) for approved biologic and pharmaceutical products in the United States and abroad.
Jeffrey represents clients during inter partes review (IPR) and appeal proceedings before the Patent Trial and Appeal Board (PTAB) and in reissues and reexaminations at the USPTO. He also assists clients with pre-litigation assessments, enforcement of patent rights, and defending against allegations of patent infringement.
Prior to joining Finnegan, Jeffrey worked as a research biologist, gaining extensive laboratory experience in microscopy and molecular biology techniques. His master’s thesis focused on the development and function of neurons in the zebrafish spinal cord. He coauthored the article, “Zebrafish V2 Cells Develop into Excitatory CiD and Notch Signaling Dependent Inhibitory VeLD Interneurons,” Developmental Biology, July 2008.
Alzheimer's Institute of America, Inc. v. Avid Radiopharmaceuticals
Member of litigation team for Avid in suit concerning amyloid beta technology and its use in animal models in searching for drugs to treat Alzheimer's disease (AD). Obtained jury verdict for Avid on issue of inventorship and patent ownership in 2012; affirmed by the Federal Circuit in 2013. Also obtained a finding of exceptional case, entitling Avid to an award of attorneys' fees. The trial disposed of a series of suits by the AIA against numerous companies involved in scientific research relating to Alzheimer's disease.
2:10-cv-06908, E.D. Pa., Judges Angell, Savage, Cohen (Special Master)
13-1544, 16-2647, Fed. Cir., Judges Hughes, Lourie, Moore, Newman, Plager
Finnegan is lead and preferred IP transactions counsel for one of the largest pharmaceutical companies in the world, handling more than 50 diligence projects each year, including all IP and related transactional aspects of the matters. The transactions span the full gamut of technologies from small molecule through biologics such as antibodies, oligonucleotides, and gene therapies. Finnegan also provides extensive assistance with post-deal integration procedures and subsequent global prosecution and portfolio strategy, ensuring a seamless transition of IP assets to the company and maximum value from acquired IP.
Global prosecution and portfolio management for major pharmaceutical company
Finnegan is lead and preferred IP strategy counsel for one of the largest pharmaceutical companies in the world, handling all aspects of prosecution and portfolio management for multiple top-tier products for the client. The work spans the gamut from drafting and prosecution through larger strategic planning, patent term extension, and pre-litigation preparation on blockbuster small molecule and biologic products in the oncology, rheumatology, immunology, neuromuscular, and cell and gene therapy spaces.
Finnegan tees up valuable patents for Eisai, leading to major strategic collaboration agreement
Kaken Pharmaceutical Co., Ltd.; Bausch Health Care v. Zydus Pharmaceuticals (USA) Inc. et al.
Successfully led Kaken and Bausch Health Care in inter partes review (IPR) proceedings, district court litigation, and Federal Circuit appeal related to patent covering Kaken and Bausch Health Care’s Jublia® (efinaconazole) product for the treatment of onychomycosis.
3:18-cv-13635, D.N.J., Judges Martinotti, Goodman
18-2232, Fed. Cir., Judges Newman, O'Malley, Taranto
IPR2017-00190, PTAB, Judges Mitchell, Franklin, Pollock
IPR2017-01429, PTAB, Judges Mitchell, Franklin, Pollock
Eli Lilly and Company v. Genentech, Inc.
PGR2019-00043, PTAB, Judges Mitchell, Paulraj, Cotta
3:18-cv-01518, S.D. Cal., Judge Sammartino
Conference
17th Summit on Biosimilars & Innovator Biologics 17th Summit on Biosimilars & Innovator Biologics
June 2-3, 2026
New York
Workshop
Protecting Innovation in the Life Sciences: Updates and Key Trends in Pharmaceutical and Biotechnology IP Law Protecting Innovation in the Life Sciences: Updates and Key Trends in Pharmaceutical and Biotechnology IP Law
May 7, 2026
Cambridge
Webinar
Top Ten Mistakes to Avoid in Negotiating and Drafting License and Collaboration Agreements Top Ten Mistakes to Avoid in Negotiating and Drafting License and Collaboration Agreements
May 6, 2026
Webinar
Conference
Life Sciences Patent Network North America Spring Life Sciences Patent Network North America Spring
April 29-30, 2026
Boston
"Jeffrey is very responsive, accommodating and a great team player."
Intellectual Asset Management Patent 1000
“Jeffrey Jacobstein and Jill MacAlpine – both are extremely responsive and always willing to help and get the job done even with tight deadlines. They are very creative and resourceful. They have great skill in drafting as well as prosecuting applications. They handle very complex cases for me and have done so wonderfully. They have a great team and work well with and use the more junior associates appropriately. They are both excellent to work with.”
Legal 500 United States
“Jeffrey Jacobstein and Eric Raciti are other experienced lead partners and sophisticated counsellors.”
Intellectual Asset Management Patent 1000
"Jeffrey is very responsive, accommodating and a great team player."
Intellectual Asset Management Patent 1000
“Jeffrey Jacobstein and Jill MacAlpine – both are extremely responsive and always willing to help and get the job done even with tight deadlines. They are very creative and resourceful. They have great skill in drafting as well as prosecuting applications. They handle very complex cases for me and have done so wonderfully. They have a great team and work well with and use the more junior associates appropriately. They are both excellent to work with.”
Legal 500 United States
“Jeffrey Jacobstein and Eric Raciti are other experienced lead partners and sophisticated counsellors.”
Intellectual Asset Management Patent 1000
Award/Ranking
Finnegan Earns Top Rankings in 2026 IAM Patent 1000 Guide; Nearly 60 Attorneys Ranked Finnegan Earns Top Rankings in 2026 IAM Patent 1000 Guide; Nearly 60 Attorneys Ranked
May 28, 2026
Intellectual Asset Management (IAM)Award/Ranking
Finnegan Shortlisted for Eight LSPN Awards Finnegan Shortlisted for Eight LSPN Awards
March 2, 2026
Life Sciences IP ReviewAward/Ranking
Finnegan Receives More Than 20 Nominations for the 2026 Managing IP Americas Awards Finnegan Receives More Than 20 Nominations for the 2026 Managing IP Americas Awards
February 11, 2026
Managing Intellectual PropertyPress Release
Finnegan Recognized as a Leading Firm in the 2025 LMG Life Sciences Americas Rankings Finnegan Recognized as a Leading Firm in the 2025 LMG Life Sciences Americas Rankings
October 1, 2025
LMG Life SciencesPress Release
Managing Intellectual Property Recognizes Three Finnegan Partners in its 2025 Rising Stars Rankings Managing Intellectual Property Recognizes Three Finnegan Partners in its 2025 Rising Stars Rankings
September 30, 2025
Managing Intellectual PropertyAward/Ranking
Finnegan Remains a Top Tier Firm in the 2025 Legal 500 Rankings Finnegan Remains a Top Tier Firm in the 2025 Legal 500 Rankings
June 11, 2025
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