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Finnegan
Jeffrey M. Jacobstein
Partner
More
vCard
  • Two Seaport Lane
  • Boston, MA 02210-2001
+1 617 646 1664
jeffrey.jacobstein@finnegan.com jeffrey.jacobstein@finnegan.com

Jeffrey M. Jacobstein

Partner

  • +1 617 646 1664 +1 617 646 1664
  • jeffrey.jacobstein@finnegan.com jeffrey.jacobstein@finnegan.com
  • Two Seaport Lane
  • Boston, MA 02210-2001
  • vCard

Jeffrey Jacobstein, managing partner of Finnegan’s Boston office, brings more than 15 years of experience in high-stakes transactions, sophisticated counseling, and successful resolution of contentious proceedings to his practice with clients in the biotechnology and life science spaces.

Jeffrey focuses on strategic client counseling, including due diligence, patent prosecution, and post-grant proceedings, with an emphasis on biotechnology and life sciences. He has led teams handling all intellectual property (IP)-related aspects of multi-billion dollar deals for several large pharmaceutical clients. His experience also includes prosecuting and appealing applications within the U.S. Patent and Trademark Office (USPTO), as well as larger portfolio management, diligence, licensing, and opinion work. Jeffrey has been recognized by LMG Life Sciences as Patent Strategy Attorney of the Year, New England, and honored for his contributions to the fields of “Patent Strategy & Management” and “Patent Prosecution.” He has also been identified by The Legal 500 U.S. as one of the leading lawyers in patent prosecution. Jeffrey previously served as leader of the firm’s patent office practice.

 

Jeffrey has conducted hundreds of evaluations for acquisition, partnership, diligence, clearance, and freedom-to-operate (FTO) assessments, and has extensive experience providing patentability, validity, enforceability, and infringement opinions. He has drafted and successfully prosecuted many new patent applications in the United States and various international jurisdictions, advising clients on all aspects of portfolio management along the way. Jeffrey also plans for and acquires patent term extensions (PTEs) and supplemental protection certificates (SPCs) for approved biologic and pharmaceutical products in the United States and abroad.

 

Jeffrey represents clients during inter partes review (IPR) and appeal proceedings before the Patent Trial and Appeal Board (PTAB) and in reissues and reexaminations at the USPTO. He also assists clients with pre-litigation assessments, enforcement of patent rights, and defending against allegations of patent infringement.

 

Prior to joining Finnegan, Jeffrey worked as a research biologist, gaining extensive laboratory experience in microscopy and molecular biology techniques. His master’s thesis focused on the development and function of neurons in the zebrafish spinal cord. He coauthored the article, “Zebrafish V2 Cells Develop into Excitatory CiD and Notch Signaling Dependent Inhibitory VeLD Interneurons,” Developmental Biology, July 2008.

 

Experience

Alzheimer's Institute of America, Inc. v. Avid Radiopharmaceuticals

Member of litigation team for Avid in suit concerning amyloid beta technology and its use in animal models in searching for drugs to treat Alzheimer's disease (AD). Obtained jury verdict for Avid on issue of inventorship and patent ownership in 2012; affirmed by the Federal Circuit in 2013. Also obtained a finding of exceptional case, entitling Avid to an award of attorneys' fees. The trial disposed of a series of suits by the AIA against numerous companies involved in scientific research relating to Alzheimer's disease.

2:10-cv-06908, E.D. Pa., Judges Angell, Savage, Cohen (Special Master)
13-1544, 16-2647, Fed. Cir., Judges Hughes, Lourie, Moore, Newman, Plager

Comprehensive patent transactions and strategic counseling for one of the largest pharmaceutical companies in the world

Finnegan is lead and preferred IP transactions counsel for one of the largest pharmaceutical companies in the world, handling more than 50 diligence projects each year, including all IP and related transactional aspects of the matters. The transactions span the full gamut of technologies from small molecule through biologics such as antibodies, oligonucleotides, and gene therapies. Finnegan also provides extensive assistance with post-deal integration procedures and subsequent global prosecution and portfolio strategy, ensuring a seamless transition of IP assets to the company and maximum value from acquired IP.

Global prosecution and portfolio management for major pharmaceutical company

Finnegan is lead and preferred IP strategy counsel for one of the largest pharmaceutical companies in the world, handling all aspects of prosecution and portfolio management for multiple top-tier products for the client.  The work spans the gamut from drafting and prosecution through larger strategic planning, patent term extension, and pre-litigation preparation on blockbuster small molecule and biologic products in the oncology, rheumatology, immunology, neuromuscular, and cell and gene therapy spaces.

Finnegan tees up valuable patents for Eisai, leading to major strategic collaboration agreement

Finnegan designed and prosecuted a global patent strategy with client Eisai on MORAb-202, an antibody-drug conjugate (ADC), providing pivotal support for Eisai’s exclusive, global strategic collaboration agreement with Bristol-Myers Squibb Company (BMS) to co-develop and co-commercialize the asset. Under the publicly announced financial terms of the agreement, BMS will pay Eisai $650 million, including $200 million as payment towards Eisai’s research and development expenses. Eisai is also entitled to receive up to $2.45 billion in potential future development, regulatory, and commercial milestones.

Kaken Pharmaceutical Co., Ltd.; Bausch Health Care v. Zydus Pharmaceuticals (USA) Inc. et al.

Successfully led Kaken and Bausch Health Care in inter partes review (IPR) proceedings, district court litigation, and Federal Circuit appeal related to patent covering Kaken and Bausch Health Care’s Jublia® (efinaconazole) product for the treatment of onychomycosis.

3:18-cv-13635, D.N.J., Judges Martinotti, Goodman
18-2232, Fed. Cir., Judges Newman, O'Malley, Taranto
IPR2017-00190, PTAB, Judges Mitchell, Franklin, Pollock
IPR2017-01429, PTAB, Judges Mitchell, Franklin, Pollock

Eli Lilly and Company v. Genentech, Inc.

Successfully represented Lilly in post-grant review (PGR) proceeding relating to patent on IL-17A/F antibodies that had been asserted against Lilly’s blockbuster Taltz® pharmaceutical and in parallel district court litigation. Achieved institution of PGR, judgment in favor of petitioner, and dismissal of the district court case.

PGR2019-00043, PTAB, Judges Mitchell, Paulraj, Cotta
3:18-cv-01518, S.D. Cal., Judge Sammartino

Insights

Conference

17th Summit on Biosimilars & Innovator Biologics 17th Summit on Biosimilars & Innovator Biologics

June 2-3, 2026

New York

Workshop

Protecting Innovation in the Life Sciences: Updates and Key Trends in Pharmaceutical and Biotechnology IP Law

Protecting Innovation in the Life Sciences: Updates and Key Trends in Pharmaceutical and Biotechnology IP Law Protecting Innovation in the Life Sciences: Updates and Key Trends in Pharmaceutical and Biotechnology IP Law

May 7, 2026

Cambridge

Webinar

Top Ten Mistakes to Avoid in Negotiating and Drafting License and Collaboration Agreements Top Ten Mistakes to Avoid in Negotiating and Drafting License and Collaboration Agreements

May 6, 2026

Webinar

Conference

Life Sciences Patent Network North America Spring Life Sciences Patent Network North America Spring

April 29-30, 2026

Boston

Webinar

Strategies for Effectively Enhancing IP Value of Critical Assets After Teva v. Amneal and Other Recent Decisions Strategies for Effectively Enhancing IP Value of Critical Assets After Teva v. Amneal and Other Recent Decisions

June 11, 2025

Webinar

Articles

Strategies for Effectively Enhancing IP Value of Critical Assets after Teva v. Amneal and Other Recent Decisions

Strategies for Effectively Enhancing IP Value of Critical Assets after Teva v. Amneal and Other Recent Decisions Strategies for Effectively Enhancing IP Value of Critical Assets after Teva v. Amneal and Other Recent Decisions

May 20, 2025

The Marker
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Professional Recognition

"Jeffrey is very responsive, accommodating and a great team player."

Intellectual Asset Management Patent 1000

“Jeffrey Jacobstein and Jill MacAlpine – both are extremely responsive and always willing to help and get the job done even with tight deadlines. They are very creative and resourceful. They have great skill in drafting as well as prosecuting applications. They handle very complex cases for me and have done so wonderfully. They have a great team and work well with and use the more junior associates appropriately. They are both excellent to work with.”

Legal 500 United States

“Jeffrey Jacobstein and Eric Raciti are other experienced lead partners and sophisticated counsellors.”

Intellectual Asset Management Patent 1000

"Jeffrey is very responsive, accommodating and a great team player."

Intellectual Asset Management Patent 1000

“Jeffrey Jacobstein and Jill MacAlpine – both are extremely responsive and always willing to help and get the job done even with tight deadlines. They are very creative and resourceful. They have great skill in drafting as well as prosecuting applications. They handle very complex cases for me and have done so wonderfully. They have a great team and work well with and use the more junior associates appropriately. They are both excellent to work with.”

Legal 500 United States

“Jeffrey Jacobstein and Eric Raciti are other experienced lead partners and sophisticated counsellors.”

Intellectual Asset Management Patent 1000

News

Award/Ranking

Finnegan Earns Top Rankings in 2026 IAM Patent 1000 Guide; Nearly 60 Attorneys Ranked Finnegan Earns Top Rankings in 2026 IAM Patent 1000 Guide; Nearly 60 Attorneys Ranked

May 28, 2026

Intellectual Asset Management (IAM)

Award/Ranking

Finnegan Shortlisted for Eight LSPN Awards Finnegan Shortlisted for Eight LSPN Awards

March 2, 2026

Life Sciences IP Review

Award/Ranking

Finnegan Receives More Than 20 Nominations for the 2026 Managing IP Americas Awards Finnegan Receives More Than 20 Nominations for the 2026 Managing IP Americas Awards

February 11, 2026

Managing Intellectual Property

Press Release

Finnegan Recognized as a Leading Firm in the 2025 LMG Life Sciences Americas Rankings Finnegan Recognized as a Leading Firm in the 2025 LMG Life Sciences Americas Rankings

October 1, 2025

LMG Life Sciences

Press Release

Managing Intellectual Property Recognizes Three Finnegan Partners in its 2025 Rising Stars Rankings Managing Intellectual Property Recognizes Three Finnegan Partners in its 2025 Rising Stars Rankings

September 30, 2025

Managing Intellectual Property

Award/Ranking

Finnegan Remains a Top Tier Firm in the 2025 Legal 500 Rankings Finnegan Remains a Top Tier Firm in the 2025 Legal 500 Rankings

June 11, 2025

The Legal 500
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Professional Activities

  • American Bar Association
    (member, Amicus Briefs Committee, Section of Intellectual Property Law, 2021-present; vice chair, Post-Grant Patent Practice and Policy Committee, Section of Intellectual Property Law, 2021-present; chair, Patents in the Chemical and Life Sciences Committee, Section of Intellectual Property Law, 2019-2021; vice chair, 2018-2019; co-vice chair, 2017-2018)
  • American Intellectual Property Law Association
  • Boston Patent Law Association
Admissions and Education

Admissions

  • U.S. Patent and Trademark Office
  • Massachusetts
  • U.S. District Court, D. Massachusetts
  • U.S. Court of Appeals, Federal Circuit

Education

Harvard Law School
J.D., cum laude, 2010
University of Cambridge
M.Phil., Developmental Biology, 2007
Harvard College
A.B., Neurobiology, summa cum laude, 2006

Jeffrey's Practices

Global IP Enforcement, Litigation, and Trials
Patent Litigation and Trials
Patent Office Invalidation Proceedings
Ex Parte Reexamination (EPR)
PTAB Invalidation Proceedings: IPR and PGR
Prosecution and Portfolio Management
Appeals to the PTAB
Due Diligence
Ex Parte Reexamination (EPR)
Freedom to Operate Opinions
IP Portfolio Management
Licensing, Pooling, and Other Transactions
Opinions and Counseling
Patent Drafting and Prosecution
Patent Mining and Mapping
Patent Reissues
Patent Term Extension (PTE) and Supplementary Protection Certificate (SPC)

Jeffrey's Industries

Life Sciences
Biologics
Biotechnology
Medical Device and Diagnostics
Pharmaceutical

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